Synthesis of Phosphonic Acids and Phosphinic Acids Derivatives toward to Biologically Active Compounds
نویسندگان
چکیده
منابع مشابه
Stereoselective Synthesis of α-Amino-C-phosphinic Acids and Derivatives.
α-Amino-C-phosphinic acids and derivatives are an important group of compounds of synthetic and medicinal interest and particular attention has been dedicated to their stereoselective synthesis in recent years. Among these, phosphinic pseudopeptides have acquired pharmacological importance in influencing physiologic and pathologic processes, primarily acting as inhibitors for proteolytic enzyme...
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Oligophosphonic and -phosphinic acids roused significant interest as complexing agents and gained importance in many fields of practical chemistry. Particular attention was drawn towards molecules having two or more phosphonic or phosphinic acid substituents in vicinal and/or preferably geminal positions attached to the ethane fragment. Novel synthetic procedures [1 -4 ] led to structures relat...
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متن کاملNew strategy for the synthesis of functionalized phosphonic acids
Various approaches leading to mono-, diand poly-functionalized phosphonates as well as phosphoryl heterocycles were reported for the systematic study of relationship between chemical structure and biological activities of this most important class of organophosphorus compounds. Introduction Functionalization of phosphonic acid molecules opens enoi-nious possibilities of structural variation of ...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 2004
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi.124.725